645 Ventures invests in early-stage startups in SaaS, infrastructure software, and consumer technologies, partnering with founders to build growth-stage businesses that reach massive scale. We champion outbound value creation by combining operational expertise with an elite network that actively influences portfolio outcomes.
We are backed by premier institutional LPs such as Princeton University, the Andrew W. Mellon Foundation, and Spelman College, as well as influential business and technology leaders who serve on the boards of companies such as Google, Facebook, Airbnb, Walmart, and American Express.
Select portfolio investments include Iterable, MM.LaFleur, Goldbely, FiscalNote, Overtime, Negotiatus, and Bespoke Post, among others. Recent portfolio acquisitions include Fly (Google), Alice (Expedia), and Source3 (Facebook).
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